In Russia created a new device for the diagnosis of cancer. A system called “Biochip” can detect whether a tumor is malignant, it is much faster than standard diagnostic methods. The analyzer can be used in the clinic, and the patient will be able to obtain the primary diagnosis after the first visit.
Work on the device leads a team of scientists from the Russian oncological scientific center (ROSC) named. N. N. Blohina, Nizhny Novgorod medical Academy and Institute of epidemiology and Microbiology them. I. N. The Blokhina. Test system consists of three component – a substrate with 15 cells, each of which is placed a specific antibody and fluorescent cells that respond to chemical reaction, scanner and containers for storage of biological material, which is a special nutrient medium with preservatives. Due to this environment, a sample from the puncture or pathological sample can be stored in the container up to a month without special conditions.
Biological sample to scroll in standard medical centrifuge, and then place a portion of the biomaterial in each of the cells. During heating up to 37 degrees, the cells may start to occur a chemical reaction of antibodies with antigens of the tumor, and if the system detects cancerous cells need a cell will glow due to the fluorescent cells. Time to reaction has taken place, very little is required, the cost of the survey is not too big – these parameters biochip outperforms existing systems.
The analyzer has already been registered in Russia, and development will be transferred under the agreement in the Asia-Pacific region. Small-scale production works in Nizhny Novgorod, and before starting the analyzer “to the masses” is not enough until the conclusion of Roszdravnadzor. The creators of the device claim that in April 2017 the biochips will be possible to start implementing the clinic.
Another analyzer has created at the Institute of theoretical and experimental Biophysics in Pushchino. It will diagnose the patient with tuberculosis in the early period, examined the pulmonary fluid obtained non-invasive way. In the study, patients breathe into a tube electrostatic collector, and the fine particles of the pulmonary fluid passing around a charged tungsten needle, also received an electric charge, and then thanks to him was moved on the graphite substrate. This substrate can be viewed via atomic force microscope and measure various characteristics of the microdroplets. Now the staff of the Institute to identify in a separate microcaps biomarkers of tuberculosis, and if this stage succeeds, it will be possible to talk about the creation of new equipment for early diagnosis.
Another two studies reported by Russian scientists, concerned a new method to measure the level of stress, and successful aging in mice. The stress appeared to affect the composition of human hair and measuring levels of the stress hormone cortisol in hair, it is possible to assess the extent of worries and cares. The method was tested on 20 women who had been diagnosed with depression, and, indeed, the lowest level of cortisol was in patients whose condition was the worst. In the second research work, scientists have significantly slowed the aging of transgenic mice by adding to their ration open the same research group before the molecule is an antioxidant SkQ1. The life span of animals increased by 15%, and they are healthier longer.