The question of “one cure, another cripple” has received a new round of development after summarizing the results of studies in Taiwan.
A number of doctors came to the conclusion that if the temperature in the cold down with ibuprofen, the risk of myocardial infarction increased 3.4 times. Other drugs with similar action — they combine in the group of non-steroidal anti-inflammatory drugs (NSAIDs) — have the same effect.
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According to the researchers, patients receive these drugs as painkillers increases the risk of heart attacks 1.5 times. That is less than a cold, but more than without them. The fact that the flu and acute respiratory viral infections (ARVI) as doctors call colds, by themselves, increase the likelihood of heart attacks by approximately 2.7 times. The indicators obtained in the result of the study, 10 of thousands of patients with similar problems.
The doctors came to the conclusion that during the colds in the body, there are processes that promote the formation of clots in blood vessels. They are the basis of many heart attacks and strokes. Loss sweat large amounts of fluid and, as a consequence, thickening of the blood, General intoxication, inflammatory effect on all the organs, including the vessels — all this together helps the formation of blood clots. Therefore, for patients with chronic cardiovascular disease so dangerous is the flu. When it all of the above processes occur most intensively. And a sick, heavy flu not tolerate.
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— This problem is known to specialists, — says Nikita Lomakin, PhD, chief cardiologist of the office of the President of the Russian Federation, head of Department of emergency cardiology of the CDB office of the President of the Russian Federation and antithrombotic Cabinet of the polyclinic CDB. — I will not say that the range is very large. For example, the doctor in their everyday activities is unlikely to be noticed the correlation between heart attacks and NSAIDs taken during acute respiratory viral infections (ARVI) or for pain relief. The more that the heart attacks associated with these drugs, does not stand out. However, when we compiled data on these patients, the relationship was found.
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What is the reason? All NSAIDs block the activity of two enzymes, abbreviated as they are called COX-1 and COX-2. The suppression of the activity of the first enzyme leads to antithrombotic activity. The blood becomes more fluid, and the formation of clots in blood vessels is difficult. This effect is used to prevent heart attacks and strokes. Millions of people around the world take this in small doses aspirin. But when it increase the dose or take other NSAIDs (to reduce the temperature in the cold or for the purpose of anesthesia), begins to dominate the second blockade of the COX-2 enzyme. And protective effect, prevents the formation of blood clots, weakening. As a result, the risk of their occurrence increases, therefore, more likely to developing heart attacks caused by blood clots in the vessels supplying blood to the heart. Primarily this relates to healthy people, and those who have risk factors for heart attack: age of 50-55 years, Smoking, overweight, high cholesterol, etc. As a rule, such people already taking to prevent small doses of aspirin or certain other drugs.
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How to protect yourself?
What you need to do in order not to increase the risk of heart attack during flu and other colds? First, it is better to reduce the temperature of medicines, and other ways. For example, as do young children. To keep the room not very high temperature, not to bundle up, the body does not overheat. You can do a wet wiping, even vodka. The liquid evaporates, cools the body. It is important to drink enough water to avoid dehydration and thickening of blood. This is also a significant factor contributing to the formation of blood clots. If not help, then the temperature it is better to reduce the drugs paracetamol or aspirin their effect on the formation of blood clots less.